

Dead Rails' latest update introduces an alchemy system where players can combine liquids to craft potent Potions. Consuming these brews grants temporary buffs and abilities to aid your survival. This guide covers all potion recipes, ingredient locations, and effects - from healing elixirs to necromantic concoctions.
Recommended Videos
Table of Contents
All Potion Recipes and Effects in Dead Rails
How to Make Potions in Dead Rails
Dead Rails Potion Tier List
All Potion Recipes and Effects in Dead Rails

The table below details every potion recipe available in Dead Rails. Simply mix ingredients on the ground, then quickly bottle the combination before it evaporates.
| Potion | Recipe | Effect |
|---|---|---|
![]() | Unicorn Blood + Blood | Angel Tears rapidly restores all health |
![]() | Unicorn Blood + Kerosene | Creates explosive flames when ignited - ideal for Arsonists |
![]() | Unicorn Blood + Water | Kills enemies with green flames while sparing allies |
![]() | Unicorn Blood + Milk | Primordial Soup revives corpses to fight for you |
Every potion requires Unicorn Blood as a base ingredient. The secondary component determines the final effect.
How to Make Potions in Dead Rails
Four mystical brews exist: Angel Tears, Devil Tears, Holy Water, and Primordial Soup. Crafting requires empty Glass Bottles found throughout the world.
Key ingredients include:
| Ingredient | Source |
|---|---|
| Water | Collect during rainstorms |
| Milk | Urban houses or Milkman class |
| Blood | Extract from slain NPCs |
| Kerosene | Drain from Molotovs |
| Zombie Blood | Harvest from undead |
| Unicorn Blood | Lightning strikes or slain unicorns |
Use empty bottles to collect liquids by clicking LMB near puddles. Press F to pour liquids onto surfaces.
Dead Rails Potion Tier List
Ranked by effectiveness for solo and group play:
| Best Group Potions | Best Solo Potions |
|---|---|
![]() | ![]() |
Angel Tears offer basic healing while Holy Water serves as weaker Devil Tears. Primordial Soup excels against zombie hordes in any scenario. Devil Tears provide outstanding crowd control with easy crafting requirements.
For helpful bonuses, check our Dead Rails codes and challenge guides.





